Canada Pharmacy Prevents the Rising Number of Cholesterol Patients

Dr. Louis Aronne, founder and director of the Comprehensive Weight Control Program at New York-Presbyterian Hospital/Weill Cornell Medical Center in New York City, was cautiously optimistic that Vivus did a good job responding to FDA safety concerns, and that the FDA will give the drug its nod of approval -- with some caveats. 

Aronne was not involved in the trials but has been an adviser to Vivus and other companies developing weight-loss medications to eliminate increasing patients with high cholesterol. If weight-loss is not your thing, then to buyWelchol for cholesterol problemsis one of the best alternatives.

"We have learned our lessons with weight-loss drugs," he said. "They need to be used in the right people under the right circumstances." The heart risks need to be weighed against reductions in heart disease risk factors that come with weight loss, he explained. Though risks associated with cholesterol are minimized, heart functions may suffer with improper weight-loss. While in the process of losing weight, Welchol 625 mg could continue to control cholesterol levels. 

"Weight-loss is no riskier than bariatric surgery," Aronne said, but it can be distributed more widely. He hopes for a compromise that allows the new compound to be prescribed but not misused. 

"Once new medications are approved, local medical boards will need to enforce rules and make sure these medications are prescribed appropriately to the right candidates," he said. "We don't want to open up pill mills." 

Dr. Scott Kahan, an obesity expert at Johns Hopkins University in Baltimore and director of the National Center for Weight and Wellness in Washington, D.C., said, "weight-loss looks promising." 

"The weight-loss effects are striking and approaching the amount of weight loss over two years that we get with bariatric surgery," Kahan said. "This is really impressive." Canada pharmacy will surely have this on stock once it is approved and launched. 

Cholesterol, from the Greek chole- (bile) and stereos (solid) followed by the chemical suffix -ol for an alcohol, is an organic chemical substance classified as a waxy steroid of fat. It is an essential structural component of mammalian cell membranes and is required to establish proper membrane permeability and fluidity. In addition, cholesterol is an important component for the manufacture of bile acids, steroid hormones, and vitamin D. Cholesterol is the principal sterol synthesized by animals; in vertebrates it is formed predominantly in the liver. Small quantities are synthesized in other eukaryotes such as plants and fungi. It is almost completely absent among prokaryotes, i.e. bacteria. 

Although cholesterol is important and necessary for human health, high levels of cholesterol in the blood have been linked to damage to arteries and cardiovascular disease. 

François Poulletier de la Salle first identified cholesterol in solid form in gallstones, in 1769. However, it was only in 1815 that chemist Eugène Chevreul named the compound "cholesterine" 

Cholesterol is required to build and maintain membranes; it modulates membrane fluidity over the range of physiological temperatures. The hydroxyl group on cholesterol interacts with the polar head groups of the membrane phospholipids and sphingolipids, while the bulky steroid and the hydrocarbon chain are embedded in the membrane, alongside the nonpolar fatty acid chain of the other lipids. Through the interaction with the phospholipid fatty acid chains, cholesterol increases membrane packing, which reduces membrane fluidity. In this structural role, cholesterol reduces the permeability of the plasma membrane to neutral solutes, protons, (positive hydrogen ions) and sodium ions.