Function and metabolism of biotin

The natural state is colorless needle-like crystals, soluble in water and not soluble in ethanol, is quite stable at room temperature. It is necessary for the animal's body to maintain normal physiological function of low molecular weight organic compounds, animal indispensable nutrients. Biotin is widely distributed in plants and microorganisms in vivo, such as wheat, brewer's yeast, alfalfa, yellow corn, barley, wheat bran, whey powder, which the biotin content in the yeast with the highest utilization. In addition, the pig large intestine microbial synthesis of biotin.

Biotin have a certain effect on the cuticle to maintain hoof strength and hardness, and limb hoof keratin and hoof integrity. In pig production, the limb hoof disease is one of the sows are eliminated, the hoof keratin the cracks were caused by the swine limb hoof diseases. Biotin nutrient metabolism and hoof horny cracks related to biotin beneficial to the health of the mother trotters Ministry. Biotin also affect the reproductive performance of sows nest litter size, conception rate and estrus interval, biotin estrus interval can be shortened to improve sow litter size, and promote the formation of uterine expansion during pregnancy and the placenta, increasing the length of the uterine horn and placental surface area. The placenta is a filter between the maternal and fetal blood system, it can select the types and levels of nutrients through the placenta barrier, after implantation, fetal growth will be mainly dependent on this filtering role of the placenta to obtain nutrients. Biotin would be better for fetal nutrition, and promote the healthy development of the fetus.

In recent years, some studies by biotin supplier of biotin on growth of piglets and pigs growth, reported that biotin can improve pig weight gain and feed conversion rate. There were also reports that the diet supplemented with biotin can improve the carcass quality of fattening pigs and its mechanism of action is to reduce the body content of unsaturated fatty acids, thereby reducing the soft fat.

Natural biotin binding and free the two kinds of forms exist, the combined forms of biotin in the gut need to biotin-degrading enzyme decomposition before animal. Biotin by diet type and composition of the pig gastrointestinal absorption. Add crystalline biotin or diets containing higher levels of available biotin pig small intestine proximal main absorption site. According to test, inject biotin to the pig's large intestine, and found to be unable to improve the content of biotin in the blood, thus suggesting that the pig's large intestine microbial synthesis of biotin, but its absorption capacity is very low.

As the cofactor to many enzymes of the body, biotin plays an important role in maintaining metabolic dynamic equilibrium, so that it could be used as cosmetic raw material. The main function is involved in the body of carbohydrates, lipids, proteins and nucleic acid metabolism involved in the function of other nutrients, such as methyl transfer reactions and other metabolic processes, and lysozyme activation and sebaceous glands, as well as vitamin B6, folic acid, pantothenic acid metabolism are closely related. Biotin is absorbed by the body and distributed in body tissue, including the highest content of liver and kidney, related to the positioning of the intracellular distribution of biotin. When the animal absorption of biotin is higher than the storage capacity, the excess part of the urine.