Two medical journals recently gave the drug Fosamax a "one-two punch" by reporting on two extremely severe side effects associated with the drug, which is used to treat osteoporosis. The drug has been associated with esophageal cancer as well as osteonecrosis of the jaw among patients.
The osteoporosis drug Fosamax was recently delivered a "one-two punch" regarding severe dangers associated with the drug. First, the New England Journal of Medicine reported that nearly 23 instances of esophageal cancer have been reported as a side effect of Fosamax. Then, in an issue of the American Dental Association, were reports that the drug's jaw die off risk is actually more common than initially thought. The jaw bone die off is actually known as a disease that affects around 20,000 Americans each year and is osteonecrosis.
The link of the most recent findings to the Fosamax drug from Merck and Co. increases the list of Fosamax risks associated with the drug since it became available on the market. Fosamax, which is the generic name for Alendronate, that became available in 2001, is often prescribed to osteoporosis patients as well as postmenopausal women who suffer from bone density loss.
An ABC news report on the drug and the recent studies speculated on the potential upcoming public perception of Fosamax and how the "one-two punch" may affect the company. One ABC News contributor, Dr. Marie Savard, said that the jaw bone die off may be "the tip of the iceberg... the drugs do change bone structure and growth."
Developing Osteonecrosis
According to the National Osteonecrosis Foundation and the Center of Osteonecrosis Research and Education, the condition commonly affects individuals between the ages of 20 and 50 years old, most often affecting individuals in their late 30s. The disease is described as "death of bone which can occur from the loss of the blood supply or by some other means." The following are potential causes of the condition:
* dislocations
* caisson disease
* sickle cell disease
* post-irradiation
* chemotherapy
* arteial disease
* gaucher’s disease
* alcohol
* lipid disturbances
* connective tissue disease
* liver disease
* kidney disease
* lupus
* smoking
* pancreatitis
* blood clotting disorders
* corticosteroids in high dosages
If an individual feels they may be a victim of the condition, there are several steps that can be taken to diagnose osteonecrosis including:
* X-ray
* magnetic resonance imaging (MRI)
* bone scan
* computed tomography (CT)
* biopsy
Details of Esophageal Cancer and Fosomax
The National Cancer Institute (NCI) defines esophageal cancer as "a cancer that forms in tissues lining the esophagus, which is the muscular tube through which food passes from the throat to the stomach." It is estimated that in 2008 approximately 16,470 individuals will suffer from a new esophageal cancer diagnosis and approximately 14,280 deaths will result from this cancer, which is a fatality rate of nearly 86 percent.
Treatments for esophageal cancer can range from surgery and chemotherapy to radiation, immuno and vaccine therapy. Additionally, the NCI reported that "when esophageal cancer is found very early, there is a better chance of recovery... and at later stages, esophageal cancer can be treated but rarely can be cured."
Receive Fosamax Assistance
Patients who currently suffer from the severe Fosamax risks can find relief by contacting a medical professional immediately to halt consumption of the drug as well as to locate an experienced medical attorney specializing in pharmaceutical dangers such as that associated with Fosamax.
Locating a pharmaceutical lawyer with knowledge of Fosamax may alleviate the pain endured by a Fosamax victim as well as increase the chances of earning monetary compensation.
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