In recent years, with the improvement of living standards of people lives, excessive drinking and excessive intake of lipids, fatty liver disease is extremely common in clinical.
But as so far there are no exact effective drugs for fatty liver. The reduced glutathione is used in the treatment of fatty liver and its efficacy is observed and compares in clinical experiments. Glutathione obtains better clinical results.
Fatty liver is fat an unusually large number accumulating in the liver, chronic liver disease. Reported in China in the past few recent years, as people's living standards improve, fatty liver, there is an increasing trend. In Shanghai medical university of China, there are 658 patients with liver diseases puncture. Among them, 55 cases have fatty liver, accounting for 8.4%. Formation of fatty liver and fat intake too much, and synthetic lipoprotein required for phospholipid and protein deficiency, malnutrition, exotic poisons and drugs, congenital, metabolic factors, most likely the main reason or liver cells fatty acid oxidation reduce the often involves mitochondrial dysfunction. B-ultrasound is non-invasive, the check is still the preferred method of diagnosis of fatty liver.
Comprehensive treatment of fatty liver treatment, must be taken, should address the different causes of treatment, such as alcoholic fatty liver, first of all should stop drinking; excess nutrients caused by fatty liver, it should be to limit sugar intake and high protein diet. Diabetic fatty liver should first control diabetes. For their treatment, data report of ursodeoxycholic acid, milk thistle is known as treatment effects. Glutathione is a natural human cytoplasmic synthesis of a tripeptide composed of glutamic acid, cysteine and glycine residues, thiol, have important physiological functions. The protective function of the liver cells. Thiol and free radicals can be transformed into easy to metabolic acids, thus speeding up the excretion of free radicals and protect from the protein, protect cell membranes, protect cells containing thiol enzyme activity, protecting cells to protect cellular DNA cells; methyl transfer and sub-alanine reaction, can protect the liver synthesis, detoxification, and inactivated hormone function, and the promotion of bile acid metabolism, gastrointestinal absorption of fat and fat-soluble vitamin (A, D, E, K), liver function markers returned to normal and maintain the effects, and lipid oxide indicators MDA level significantly reduced.
Using pharmaceutical raw materials reduced glutathione in the treatment of fatty liver can achieve better clinical results. In treatment group of 42 patients, after the application of this drug, the clinical symptoms are rapidly improved and B ultrasonic examination show significant improvement in liver sonogram. Among them, serum ALT, AST of 30 cases return to normal levels. There are 8 cases whose serums ALT, AST are significantly decreased (lower than 50%). Four cases have no significant changes. The total effective rate is 90.5%. The research shows that using glutathione in treatment of fatty liver on the basis of comprehensive treatment, the liver function parameters will return to normal and it has an apparent efficacy in a short period of time.Source:http://www.cospcn.com
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