Research Confirms Safety Of Hyaluronic Acid

A study published in the February 2007 issue of Food and Chemical Toxicology has confirmed the safety of oral hyaluronic acid. 

Hyaluronic acid is a dietary supplement that supports connective tissue health in joints and skin. The research was comprised of two oral toxicity studies involving acute and subchronic tests. Test subjects exhibited no toxicity, even at 33 times the recommended dose, as observed by a review of a variety of biomarkers and histopathological examinations. The publication - which only publishes high-quality research to assist in health and safety decisions - disclosed that the wide variety of toxicity studies performed on the ingredient affirmed hyaluronic acid to be safe for use as an oral health food supplement.

Researchers tested the patented, dietary supplement, BioCell Collagen II, which is composed of a minimum 60 percent Hydrolyzed Collagen Type II, 20 percent Chondroitin Sulfate, and 10 percent Hyaluronic Acid (HA). As a particularly rich source of bioavailable hyaluronic acid, it works to promote joint and skin health.

BioCell Technology Vice President Suhail Ishaq said in a press release, “The affirmation on the safety of BioCell Collagen II reflects a significant advance in today's health food industry. BioCell Collagen II is the only dietary ingredient of its kind to undergo the rigors of toxicity testing. Consumers can be confident about the safety BioCell Collagen II, and it opens the door to new product development in the functional foods market. With this toxicity study behind us, along with other studies that we have commissioned, our next goal is to achieve GRAS certification.”

Source: Schauss, A.G., Merkel, D.J., Glaza, S.M., Sorensonet, S.R., et al. (2007). Acute and subchronic oral toxicity studies in rats of a hydrolyzed chicken sternal cartilage preparation. Food and Chemical Toxicology, 45 (2), 315-321.