The world is really wonderful. On one hand, the caucasian advocates tan tanning. While on the other hand, people with darker skin have been looking for white magic pills.
Topical, oral, or intravascular injection of a variety of whitening ingredients, are now widely used by cosmetic raw material suppliers in the market. Many topical compositions play the role in melanin biosynthesis. The sunscreen ingredients are also widely used for facial whitening.
With the needs of the body whitening oral composition also popular, tranexamic acid is one of them (popular in the Asian region, especially in Japan). Oral methotrexate bad acid (a protease inhibitor) whitening, and its long-term security, the current lack of sufficient evidence to support. Another oral whitening ingredients are glutathione, by influencing the activity of tyrosinase inhibition of melanocyte generation; more importantly, when glutathione or cystine for black flaky cells or melanoma cells, of melanogenesis channel from the formation of eumelanin into a false melanin.
After oral administration, glutathione’s gastrointestinal absorption is poor. So in many countries (especially for Southeast Asian countries), glutathione has been used for vascular injection. Recently, intravascular injection of glutathione whitening popular in Thailand, to prevent serious allergic reactions, the government is considering to be prohibited. In this context, the efficacy of oral glutathione whitening randomized, double-blind, placebo-controlled study to determine whether oral glutathione affect the skin melanocyte index.
The experiment randomly selected 60 patients, divided into the treated group and control group, a trial period of four weeks. Melanocyte determination in six parts of the body (including the face, arm board exposed to sunlight and not exposed parts) Determination of melanocyte index to reduce the average amount. VISIA imaging system records. After 4 weeks, all subjects of the treated group the six parts of the body melanocytes index reduced. Right cheek and left forearm (by sunlight parts), melanocyte index decreased significantly compared with placebo medication group, and tolerance are good.
According to the research, small-scale test of oral glutathione has effect on the color. However, its safety needs confirmed in more extensive clinical trials. It is worth noting that glutathione melanocyte only plays a role on both pigment. But these drugs did not help to change the pathological process of pigmentation (chloasma, natural color). It is a good idea to prevent pigmentation. Glutathione oral dosage forms; effect part is pretty good - if a lot of use, can be done almost similar to the sun black. The so-called large-scale use, it is not marked dose. However, the generally recommended dose is one to two day, can minor Hacking. If you use four a day, you can take the initiative to whitening.
For melasma, glutathione also has good efficiency. The drawback is that it is disabled after the stopping taking. Hepatitis as one of China's national diseases, it is treated by confused use between milk thistle extract and glutathione and. Some obese patients with fatty liver use them for curing the disease. After four to five days, the liver function index decreased quite significantly. The smelling of the mouth, the hot feelings are vastly improved. These two ingredients are very important to the liver. Source:http://www.cosprm.com
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