Types of Antedepressants

Antdepressants can be classified on the basis of how they affect the chemicals presents in our body, which are the main cause of depression. On the basis of these chemicals, the antedepressants can be classified in the following classes:

Selective Serotonin Reuptake Inhibitors (SSRIs): One of the main causes of depression is the reduction of the serotonin, which are consumed by presynaptic neuron. Serotonin is used by brain to send the signals to neurons. SSRIs prevent the consumption of serotonin, and thus maintain high level of serotonin. SSRIs include fluoxetine, paroxetine, escitalopram, citalopram and sertraline. Herbal Remedy increases its production in the body and thus reduces depression.

Monoamine Oxidase Inhibitor (MOI): MOIs reduce the depression by blocking the monoamine oxidase enzyme. MOIs are effective in the treatment of depression they have some serious side effects. The individuals taking MOIs have to be careful with their diet and avoid the intake of alcohol.

Augmenter drugs: These drugs are the combinations of one or more drugs such as tryptophan, buspirone and tranquillizers, sedatives. Tranquillizers and sedatives are helpful in curing anxiety, but they are addictive. Therefore, they are rarely used.

Newer mechanisms: There are five antepressants, which can not be included in any of the above categories. These antepressants are as follows:

Bupropion: It is used in the treatment of severe and seasonal depressions. It should not be used in case of epilepsy and eating disorders. It should not be prescribed to individuals less than 24 years of age as it increases the suicidal attempts.

Nefazodone: It is helpful in curing depression, but is harmful for the liver. The continued use of nefazodone can lead to liver ttransplant or even death in some cases.

Venlafaxine: It is used in the treatment of anxiety disorders, panic disorder and clinical depression. However, it also has side effects, which includes the attempt to suicide by the individual.

Mirtazapine: It is used in the treatment of moderate as well as severe depression. The side effects of mirtazapine is drowsiness and weight gain. It is safe even if it is overdosed.

Trazodone: It is used in the treatment of anxiety depression. It can also be used in panic and eating disorders. It should not be prescribed to children below 18 years of age as it can lead to suicidal attempts.