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Acne is a skin condition that causes whiteheads, blackheads, and inflamed red lesions (papules, pustules, and cysts) to form. These growths are commonly called pimples. Acne occurs when tiny holes on the surface of the skin, called pores, become clogged. Each pore is an opening to a canal called a follicle, which contains hair and an oil gland. Normally, the oil glands help keep the skin lubricated. When glands produce too much oil, the pores can become blocked, accumulating dirt, debris, and bacteria. The blockage is called a plug or comedone
CAUSE & CONTRIBUTING FACTORS
Normal Follicles:
Sebum produced by the sebaceous gland combines with cells being sloughed off within the hair follicle and "fills up" the hair follicle. When the follicle is "full", the sebum spreads over the skin surface giving the skin an oily appearance.
Obstructed Follicles
When the sebum is trapped in the hair follicle causes plugging up the follicle. The process of obstructing follicles is called cosmogenesis. It causes some follicles to form a type of acne called comedones, also known as blackheads and whiteheads.
Propionibacterium acne:
Propionibacterium acnes is a bacterium that lives on your skin and uses the sebum as nutrients for its growth. The sebaceous glands are hypersensitive to androgens that cause enlargement of the gland and more sebum secretion. In puberty, the androgens hormone is secreted more and thus there is more sebum secretion and more Propionibacterium acnes in the follicle. The presence of P.acne attracts WBC to the follicle and thus an inflammatory reaction is settled up.
No one factor causes acne. Several factors can contribute to the cause of acne
Changing Hormone Levels
For most people with acne, it begins at puberty. This is when the body starts to produce hormones called androgens. Androgens cause the enlargement and overstimulation of the sebaceous glands. Sensitivity to these androgens also causes acne to appear during the menstrual cycle and sometimes in pregnancy. Starting or stopping birth control pills can also cause acne.
Stress
Severe or prolonged emotional tension and stress may aggravate the Acne condition. Stress causes the production of hormones, such as cortisol, which can aggravate acne.
Drugs:
Some medications may cause acne, such as anticonvulsant drugs, lithium, bromides, or oral or injected steroids. Most cases of acne, however, are not drug-related.
Skin Care Products
Some cosmetics and skin-care products are pore-clogging. The skincare products which have the ingredients ‘water based’ are usually safe.
PATHOGENESIS OF ACNE
There are 4 basic factors involved in the development of acne.
Acne arises due to blockage of follicles, the sebaceous follicles which are found in the face, neck, chest, and/or back. In acne patients, the sebaceous glands attached to these follicles secrete excessive amounts of sebum. It has been shown that the sebaceous glands in acne patients tend to be hyperresponsive to androgens, which are first released in the prepubertal period. Thus, these patients produce more sebum than is normal; this excessive secretion is a necessary prerequisite for the onset of acne.
Second, the epithelial cells (keratinous squamous cells) lining of the innermost layer of the follicles undergoes abnormal desquamation. The cause why it happens is unknown. Normally, keratinous squamous cells are loosely organized in the normal follicles, but they become denser and more coherent as a result of abnormal desquamation. The combination of abnormally desquamated cells and excessive sebum forms a “plug,” or microcomedo — the precursor lesion of both noninflammatory comedones and inflammatory lesions.
Third, the propionibacterium acne is a bacterium that lives on your skin and uses the sebum as nutrients for its growth. The sebaceous glands are hypersensitive to androgens that cause enlargement of the gland and more sebum secretion. In puberty, the androgens hormone is secreted more and thus there is more sebum secretion and more Propionibacterium acnes in the follicle. The presence of P.acne attracts WBC to the follicle and thus an inflammatory reaction is settled up
Fourth, P acnes produces pro-inflammatory mediators and chemotactic factors that can cause microcomedones to inflame and evolve into papules, pustules, and nodules.
HOW HOMEOPATHY HELPS
Constitutional homeopathy treatment not only treats the acne condition but also treats the whole patients as a whole
https://www.multicarehomeopathy.com/diseases/Cause-of-Acne-and-Homeopathy-Treatment-for-acne
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