Study researchers have established three new genomic regions they deem associated with breast cancer that may help illustrate why some females acquire the illness. In lieu, new and more effective Canadian drugs will surely hit the market.
Study researchers have established three new genomic regions they deem associated with breast cancer that may help illustrate why some females acquire the illness. In lieu, new and more effective Canadian drugs will surely hit the market.
All three newly identified areas "contain interesting genes that open up new avenues for biological and clinical research," said researcher Douglas Easton, a professor of genetic epidemiology at the University of Cambridge in England.
"The three [newly identified] loci take the number of common susceptibility loci from 22 to 25," said Douglas Easton, Ph.D., professor, genetic epidemiology, University of Cambridge, England.
"However, the three new susceptibility loci might explain only about 0.7 percent of the familial risks of breast cancer, bringing the total contribution to about 9 percent," the researchers said.
Michael Melner, scientific program director for the American Cancer Society, said "this current research adds some important new clues to existing evidence, but he agreed that the number of cases likely associated with these three variants is probably low."
"So the total impact in terms of patients would be fairly small," Melner said.
"Easton's team found that the variant on the 12p11 chromosome is linked with both estrogen receptor-positive breast cancer (which needs estrogen to grow) and estrogen receptor-negative breast cancer. The other two variants are only linked with ER-positive cancers," they said. It is suggested to buy Evista in order to prevent development of breast cancer after menopause.
"One of the newly identified variants is in an area with a gene that has a role in the development of mammary glands and bones. Easton said it was already known that mammary gland development in puberty is an important period in terms of determining later cancer risk. But these are the first susceptibility genes to be shown to be involved in this process," he said.
"When you delineate a pathway, you bring up new potential targets for therapy," he said. "The more targets you have, you open up the potential for having multiple drugs and attacking a cancer more easily, without it becoming more resistant."
Overall, Melner added, "the results underscore the complexity of the different mechanisms involved in breast cancer development." In every complexity identified, the Canadian pharmacy nearest you has the corresponding meds for treatment.
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