Banti's Syndrome, also known as Banti's disease, is an illness characterized by an enlargement of the spleen with anemia. These terms were actually used more in the past then they are today.
Banti's Syndrome actually covers a variety of disorders. Korovnokov's syndrome, a special form of Banti's disease characterised by splenomegaly with subthrombocytosis and gastrointestinal hemorrhage. Banti's syndrome is a chronic congestive enlargement of the spleen resulting in premature destruction of the red blood cells by the spleen. It is most frequently in females under 35 years of age, and affects either sex.
In some instances of the disease, it seems to be produces by a large clot forming in the veins of the spleen or because of increased pressure within the veins in the spleen as a result of liver disease. Enlargement of spleen, ascites, jaundice, and the result of destruction of various blood cells by spleen - anemia,leukopenia, thrombocytopenia, gastrointestinal tract bleeding - may constitute the presenting symptoms. The disorder may be due to any number of different factors causing obstruction of portal, hepatic, or splenic veins including abnormalities present at birth (congenital) of such veins and blood clots.
This condition is often create and diagnosed in babies and children and may show signs of anemia, higpertension and jaundice (a yellow tinge to the coloring of the skin.). Treatment may involve various surgical procedures. For instance, where the disease is due to increased pressure within the veins leading to the spleen, surgical shunting procedures will likely be conducted. This will help create artificial means of joining the veins to decrease the blood pressure. Treatment options, however, will depend on the exact nature of the enlargement of the spleen, as well as any other health concerns or conditions that may be present also.
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