Degos Disease seems to be a disease of the blood vessels.
Degos disease, also known as malignant atrophic papulosis is a rare disorder. It generally occurs in young Caucasian adults. Degos disease is rare, but in the known cases females have been affected more often than males. Degos disease affects the lining of the small blood vessels resulting in occlusion (blockage). The blood vessels affected include those supplying the skin, gastrointestinal tract and central nervous system. Degos disease usually progresses through two stages. During the first stage, characteristic skin lesions appear that may last for a period of time ranging from weeks to years. Second stage of Degos disease is most frequently characterized by lesions in the small intestine.
Major symptoms may include abdominal pain, diarrhea, and/or weight loss. Degos disease usually causes a distinctive rash, which is often its first symptom. The rash develops slowly, beginning as pink or red bumps (papules) that are 2-15 mm in diameter. Degos disease may affect the gastrointestinal system, causing abdominal pain, distention, cramps, nausea, vomiting, diarrhea, or constipation. The Cause degos disease include a virus, an immune defect, or a clotting defect. Tried different medications, such as aspirin or dipyridamole, with some success, but no one medication has yet proven always effective in relieving or reducing symptoms. Other treatments include topical corticosteroids, phenformin and ethylestrenol, iodohydroxyquinoline, aspirin and dipyridamole, phenylbutazone, arsenic.
Degos Disease - Prevention and Treatment Tips
1. Anti-platelet drugs like aspirin and dipyridamole may reduce the number of new lesions in some patients.
2. Surgery may be necessary.
3. Topical corticosteroids is also treat Degos
4. Other treatment is phenformin and ethylestrenol.
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