Biological oxidation reaction is the basic physiological and biochemical processes for each cell in vivo, is very important to maintain normal metabolism. Biooxidation process will generate the oxygen free radicals, water and active oxygen, active oxygen with high degree instability, the excess of reactive oxygen species can cause oxidative damage, resulting in amino acid being oxidized, protein degraded and DNA damage and so on.
Oxygen radicals also attacks fatty acids on the cell membrane, oxidized fatty acid through chain reaction to produce more fatty acid radical. The presence of excessive free radicals break the balance of biological free radicals and antioxidants, an important factor in causing rheumatoid arthritis, cardiovascular and cerebrovascular disease, Parkinson's disease, cancer.
Astaxanthin is a natural pigment, is one kind of carotenoid, belonging to the strand breaks anti-oxidant, with strong anti-oxidation. Over the years, astaxanthin has been as a common plant pigment did not attract too much attention.
Scientists compared it with the carotenoids and their derivatives which the structure is similar, but the conjugated double bonds are different, such as: lutein, zeaxanthin, astaxanthin pigment, iso zeaxanthin. Found that in the oxidation of carotenoids and their derivatives, quenching inactivated oxygen increasing with conjugated double bonds increasing, wherein the strongest antioxidant is astaxanthin. The test confirmed that the antioxidant effect of astaxanthin is stronger than ±-vitamin E thousandfold more, and also can effectively prevent the peroxide of phospholipids and other lipid. Recent studies by astaxanthin suppliers have found that astaxanthin has superior physiological functions, it not only has the efficacy of anti-cancer tumor suppressor, but also has significance for the prevention of cardiovascular disease, atherosclerosis, such as a variety of other diseases, strengthens the immune system, as well as anti-aging. The chemical properties of astaxanthin determines it has the function of anti-oxidation, inhibition of mutations, reducing nucleic acid damage.
Astaxanthin can accept different electronic excited state energy, absorb and through singlet energy transfer. A astaxanthin molecule may clear thousands of singlet oxygen, its quenching rate constant of singlet oxygen is 2 times higher than ²-carotene. Astaxanthin can also eliminate by the chemical reaction of reactive oxygen species and other forms of oxidative free radicals, and oxidative free radicals can cause lipid peroxidation to form a variety of products, these products are related to human aging, cancer, autoimmune disease and anemia. Astaxanthin on cell growth and metabolism plays a regulatory role, usually cell gap between membrane proteins constitute the channel, with selective permeability, allowing second messengers and growth regulator substances through gap junctional communication between cells, transfer cells population growth regulatory signals regulating normal cell proliferation and differentiation. The experiments show that the astaxanthin through the induction of cell-cell connection, enhanced GJIC between the normal cells, control of cell growth and induction of cell differentiation to inhibit tumor growth.
In addition, astaxanthin has the function of preventing osteoporosis, lower blood pressure, improving the male and female reproductive, reducing exercise-induced asthma and other physiological functions. Astaxanthin can greatly improve skin allergies, get rid of dry skin caused skin allergies and itching sensation. And so far, there are not reports found that taking astaxanthin have side effects, and therefore it is very suitable for long-term taking.
Haematococcus pluvialis, as the best biological raw material for the production of natural astaxanthin in nature, has caused widespread concern in the international field, the nurturing and development of technology is improving daily, astaxanthin in cosmetics material and medicine has broad prospects for development undoubtedly.
Source:http://www.cosprm.com
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