There are at least 8 to 9 species of anti-cancer drugs in international market. But none of them reach 200 million U.S. dollars sales in the next year after they are listed in market like paclitaxel
The cumulative sales of paclitaxel have exceeded $ 20 billion so far since 1992. It is estimated that its total global sales were approximately $ 4.5 billion last year.
Production and export of taxol bulk drugs is growing rapidly in recent years. The international market makes the paclitaxel price from $ 600,000 per kilogram dropped to $ 400,000. If the Chinese yew tree plantations completed and put into Taxol, paclitaxel on the international market prices to fall further in the future. China is expected to become the world's largest producer and exporter of paclitaxel.
European medical researchers from Europe, widely cultivated in Europe, the tender foliage ornamental yew extract taxol intermediate raw materials, the synthesis and the benzoyl group, paclitaxel analogue docetaxel. Docetaxel is not only excellent water-soluble and clinical studies have shown that the bioavailability and anti-cancer effect is even better than paclitaxel. Since then, docetaxel quickly became the best-selling variety of international anti-cancer drugs on the market. So docetaxel cost is always rising. At present, sales of semi-synthetic paclitaxel are overwhelming sales of paclitaxel. Since 2000, many countries including China have adopted a semi-synthetic method for production of paclitaxel.
United States is still trial taxus cell culture method to produce paclitaxel, but not the formation of large-scale production, the production of paclitaxel was estimated at most tens of liters per year. So far, the use of global production of paclitaxel stills Both of yew bark extraction, yew branches extraction and semi-synthetic method, the yield of the latter.
Taxol is a drug commonly used to the world medical community for cancer treatment, not only doctors willing to use, and patients to its tolerance are also very good, the only drawback is its higher retail price. China and the United States, like the world cancer of high incidence countries, estimated national lung cancer and breast cancer patients together there are at least hundreds of thousands of the public, specifically paclitaxel for the treatment of lung and breast cancer will become China's top-selling drugs. Insiders predicted that China paclitaxel in the future retail price dropped to less than 200 RM for each one. The paclitaxel market sales will be increased by 5 to 10 times in this year.
Pharmaceutical raw materials suppliers have predicted that there will no anti-cancer drugs found which are better than paclitaxe in the next few years. So paclitaxel will remain its position of backbone product in international anticancer drugs market. Its dominant market position is unshakable.Source:http://www.cospcn.com
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