Scientists’ recent animal studies though that dietary intake of resveratrol by preventing the formation of adipose tissue to reduce the amount of body fat. The study found that fed a high-fat diet to rats, despite the weight of the two groups of mice is similar, but added the resveratrol group mice, their body fat is less than not added resveratrol.
In this study, researchers used 16 rats and divided into two groups, fed the same diet, one of the group added 30mg/kg weight/day dose of resveratrol in the diet. For six weeks. The results show that the weight of the two groups of mice is similar, but the fat content of the resveratrol group mice was significantly lower than the control group. The researchers found that mice fed resveratrol, the related activity with fat is decreased, response to decreased activity with the blood triglycerides fatty acids increase. Although the present study come up with a mechanism, but the related mechanism still needs further research. The study reveals the potential of resveratrol might be used to eliminate the fat, and if the results can be reproduced in other studies, especially in human clinical studies, it will extend the application field of resveratrol.
According resveratrol supplier, resveratrol is an ingredient present in cuspidatum and grape, French scientists in 1992 made the famous "French paradox" and attract the attention of the industry and a lot of researches. 2003 Harvard study shows that it may be extended a variety of biological life. Introduction of food and beverage products containing resveratrol increased. A recent market survey shows that from 2009 to 2010, the launch of resveratrol-containing foods and beverages increased threefold.
In addition, the latest research by Danish scientist shows that resveratrol can change the hormone production of fat cells in human fat cells, and provides anti-inflammatory effects, which can improve the metabolism of obese people. The in vitro study is the first time to show that resveratrol has the anti-inflammatory effects on fat cell hormone expression and human adipose tissue secrete.
Pharmaceutical raw materials suppliers expect the anti-inflammatory effect of resveratrol is capable of effective low-level inflammation associated with obesity. Inflammation characterized by abnormal proinflammatory response factor circulating abnormal and adipose tissue activity factor. These factors will directly affect the occurrence of the metabolic syndrome. In this new study, the researchers examined the effects of resveratrol in human adipose tissue explants interleukin-1beta (IL-1B). The study found that when the human cells in the IL-1B, the secreting of cells inflammatory compounds IL6, IL8, MCP-1increasing. When these cells are placed resveratrol, the active material of these cells secret reduced 16% -36%.
Accordingly, the researchers said, the results show that resveratrol can improve the production and expression of proinflammatory cytokine in human adipose tissue, increasing the body's protective effect, reducing the occurrence of the metabolic syndrome in obese patients. However, due to the environment in vitro and in vivo environment is big difference, it is difficult to simulate, therefore need further study on the effect of resveratrol. In addition, due to the oral dosage form resveratrol is quickly absorbed and quickly metabolism, thus their in vivo can reach to produce this effect as well as whether the uronic resveratrol can achieve this effect and its use of concentration need to do further clinical studies.
Source:http://www.cospcn.com
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