Magic Mushrooms and Canadian Drugs Relieve Depression

According to a recent study, psychedelic mushrooms and new Canada drug s may lead to new manners of treating depression. 

"Psychedelics are thought of as 'mind-expanding' drugs, so it has commonly been assumed that they work by increasing brain activity, but surprisingly, we found that psilocybin actually caused activity to decrease in areas that have the densest connections with other areas," according to David Nutt, who's with the Department of Medicine at Imperial College London, was the senior author of both of the new studies. "These hubs constrain our experience of the world and keep it orderly. We now know that deactivating these regions leads to a state in which the world is experienced as strange." 

The impact of psilocybin reported by the study participants -- such as seeing "geometric" patterns, experiencing an altered sense of time and space, and unusual physical sensations -- correlated with a decreased flow of oxygen and blood to parts in the brain's posterior cingulate cortex and medial prefrontal cortex (mPFC), the study authors said. 

It's thought that the posterior cingulate cortex plays a role in consciousness and self-identity. Research has shown the medial prefrontal cortex to be especially active in people struggling with depression, so psilocybin's effect on this area of the brain could be responsible for some of the antidepressant effects reported in previous research, the study authors said. 

"Psilocybin was used extensively in psychotherapy in the 1950s, but the biological rationale for its use has not been properly investigated until now. Our findings support the idea that psilocybin facilitates access to personal memories and emotions," Dr. Robin Carhart-Harris, from the Department of Medicine at Imperial College London, and first author of both studies, said in the news release.  For the meantime, it is recommended to buy Celexa for the treatment of symptoms of patients with depression. 

"Previous studies have suggested that psilocybin can improve people's sense of emotional well-being and even reduce depression in people with anxiety. This is consistent with our finding that psilocybin decreases mPFC activity, as many effective depression treatments do. The effects need to be investigated further and ours was only a small study, but we are interested in exploring psilocybin's potential as a therapeutic tool," Carhart-Harris added.  With this, it is possible to design meds with this newly discovered remedy and have them available at various Canadian pharmacies .