Minoxidil was a drug used to treat hypertension originally in the 1970s, classified as Potassium Channel Openers, and has effects on expansion of peripheral vascular, such study of potassium channel openers was doing for many years.
Minoxidil is the only widely used drugs in the human body. Hirsutism, hair or non-expected growth was originally the side effects of this drug, but also because of the inspiration of such side effects, minoxidil is imported for the treatment of male and female alopecia. Today, Cosmetics material minoxidil is develop into two forms of drugs, oral minoxidil is used to treat high blood pressure; and topical minoxidil was used in the treatment of hair loss and baldness. Concentration of 2% topical minoxidil in the United States in 1986, after seven years, the concentration of 5% also be listed.
Through animal experiments confirmed that the stump-tailed macaque body minoxidil can shorten the hair follicle resting stage, the static in the hair follicles to enter the growing season earlier, minoxidil can really add a certain percentage of hair follicles in the histological study of these primates display enter the growth phase, and reduce the number of telogen hair follicles; can also increase the size of the hair follicle itself, so the hair becomes more coarse. In human trials, minoxidil for hair growth cycle have the same effect, increasing hair diameter is also possible to happen.
Why minoxidil germinal efficacy? In fact minoxidil is not the function of anti-androgen, in animal studies, minoxidil does not stimulate testosterone or adrenal androgen secretion; on human experimentation, the serum testosterone concentration will not change because of the use of minoxidil. However, according to the results of clinical trials, with male pattern baldness hair loss in men and women, hair re-use minoxidil, hair quantity and weight are significantly increased. Because minoxidil can make the tiny hair follicles to produce a reversal of the role of renewable and let the hair to accelerate growth and promote the key to enter the growth phase of hair follicles from the telogen. If minoxidil resolution as a vasodilator, with so increase the flow of blood flow to the hair follicles to stimulate hair growth results
The composition of the skin from the outside, mainly three parts of the epidermis, dermis, subcutaneous tissue. The epidermis is the outermost layer, the thickness is only about 0.5mm. It is mainly composed of layers of keratinocytes, and keratinocytes can protect the body from intrusion by the external environment or micro-organisms and maintain a certain humidity and moisture. We have confirmed that the minoxidil is good for the growth of keratinocytes, primate and human hair regeneration, and have the positive effect. Germinal effects, buy minoxidil and the use of products containing minoxidil, usually 6-8 weeks, you can begin to see the increase of hair, can see noticeable results in 12-16 weeks. But not everyone is applicable to the above effective period, sometimes after the first out of the hair increased, and increased hair is not always grow to the general coarse hair types, there are likely to grow finer hair.
Source:http://www.cosprm.com
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